Micro-CT for Pharmaceutical Research

SKYSCAN 3D X-ray microscopes are essential tools for R&D and product development in the pharmaceutical field. Accelerate drug development and inspection, increase quality control and gain better insight of defects in manufacturing, or verify packing and coating integrity.  

  • Nano-meter scale resolution for detailed porosity calculations
  • High contrast on low X-ray absorbing phases including active pharmaceutical ingredients and coatings
  • Large field of view for capturing full pharmaceutical tablets
  • Quantitative analysis for pore size, pore size distribution, and volumetric API calculations
Tablet compression

Full tablet imaging

The large field-of-view detectors of the SkyScan instruments allow for routine scanning of full tablets at high resolution. 

Pharmaceutical - pill delamination

Porosity analysis

Pore size, pores size distribution, and pore orientation are key metrics for understanding the performance of the manufacturing process and the resultant API delivery. These measures can be calculated in the CTAN quantitative analysis program. 

Crack analysis of pill

Crack and delamination analysis

Through the use of the latest detection architecture, the SKYSCAN tomographs can deliver high quality images of internal cracks in the tablet and subsurface delamination of coatings or under debossed regions.  

In-situ compression testing of pill

In-situ compression testing

All SkyScan instruments are pre-wired to accept the in-situ materials testing stages.

Related Articles

Micro-CT Imaging of Samples Under Mechanical Load

Figure 1: 3D Printed Support Structures After Mechanical Load Testing  As an accessory to the SkyScan instrumentation suite, Bruker offers several interesting accessories that can further support your research goals.

Not sure about the best instrument for your application?
Do you want to see micro-CT results of your sample?
Our specialists are happy to help.
Not sure about the best instrument for your application?
Do you want to see micro-CT results of your sample?
Our specialists are happy to help.

Micro-CT Buyers' Guide​








    Free Micro-CT Evaluation Scan

    Are you interested in Micro-CT but aren’t sure if it will work for your application?  We would be happy to help you determine if a micro-CT is right for you and guide you to the system that is best suited for your application.  Our micro-CT laboratory has five different Bruker SkyScan Micro-CT systems available for a thorough investigation of your sample.

    Micro-CT results

    Send in a sample and our micro-CT experts will do the rest.  We will select the best instrument, scan the sample, and reconstruct the data.  You will receive a series of cross-sectional images visualizing the interior structure, a 3D model of your results and  a video of your sample with cut-through views. We will also provide our visualization software for enhanced viewing in both 2D and 3D … Explore Within!

    Fill out the form below and will we contact you to arrange the free micro-CT scan.








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        Employment

        Service Engineer opening for Micro-CT Systems

        We are looking for a service engineer to join our team of experts in helping advance research by providing technical support and maintenance for micro-CT systems across the United States.
        JOB DESCRIPTION

        Please submit resumes to: info@microphotonics.com

        Micro Photonics Inc.
        1550 Pond Road, STE 110
        Allentown, PA 18104

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