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    SkyScan 1276 Micro-CT | in-vivo 3D imaging

    SkyScan 1276 : A High Resolution, Fast In-Vivo Micro-CT Scanner

    In-Vivo Micro-CT Description

    The SkyScan 1276 Micro-CT is a high performance, stand-alone, fast, desk-top in vivo micro-CT with continuously variable magnification for scanning small laboratory animals (mice, rats, …) and biological samples. It has an unrivaled combination of high resolution and large image size; it has the option for round and spiral (helical) scanning and reconstruction, and low dose imaging. The image field of view (up to 80 mm wide and more than 300 mm long) captures the full body  of mice and rats. The variable magnification allows scanning of bone and tissue samples with high spatial resolution down to 2.8 µm pixel size. Variable X-Ray energy combined with a range of filters ensures optimal image quality for diverse research applications from lung tissue to bone with metal implants. Additionally, the SkyScan 1276 in-vivo micro-CT administers low radiation dose to the animals allowing for multiple scans in longitudinal preclinical studies without the risk of unwanted radiation – induced side effects. The system can perform scanning with continuous gantry rotation and in step-and-shoot mode with a fast scanning cycle of 3.9 sec.

    The SkyScan 1276 allows for the non invasive reconstructing of any cross section(s) through the animal body with possibilities to convert the reconstructed dataset into realistic 3D-image and calculate internal morphological parameters including specific bone structural parameters.

    Interchangeable Mouse and Rat Cassettes

    The SkyScan 1276 system is supplied with exchangeable animal cassettes that can be used in all Bruker in-vivo imaging instruments such as MRI, micro-PET, micro-SPECT, bio-luminescence, biofluorescence, etc. to collect multimodal information. It allows co-registration of functional and morphological information from the same animal.

    interchangeable beds

    Touchscreen Control

    The user interface of the SkyScan 1276 in-vivo micro-CT system is simple and intuitive. The instrument can be controlled from the computer screen and also from the embedded force-sensitive touchscreen, which can be operated by gloved hands. The touchscreen allows selection of scanning protocol, adjusting the animal bed position and control of imaging and scanning. Where multiple scans are started from the touchscreen, the software will automatically save acquired data to separate subfolders with incrementally assigned folder names and dataset file prefixes.

    in-vivo micro-CT touchscreen control

    For high resolution Ex Vivo scanning be sure to check the SkyScan 1272.

    The full range of SkyScan software is supplied, including fast volumetric reconstruction, software for 2D / 3D quantitative analysis and for realistic 3D visualization. The software for 4D time-resolved microtomography is also supplied as standard. The scanner can work in “push button” mode with scanning start/stop and protocol setting from the integrated touch screen. The touch screen has a force sensitive surface allowing normal response while wearing gloves. The main control rack-mounted workstation is integrated below the scanner. The scanner can be optionally supplied with an integrated cluster of four powerful workstations placed in the lower part of the scanner’s body.


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    • 3.9 seconds shortest scanning cycle
    • 2.8 micron highest nominal resolution
    • Spiral (helical) and round scanning
    • 11 Mp cooled X-ray camera
    • Integrated physiological monitoring (breathing, movement detection, ECG) for time-resolved 4D microtomography
    • On-screen dose meter to estimate accumulated dose and dose rate
    • System is supplied with an advanced gpu-accelerated reconstruction program that can be used for circular or helical scan trajectory reconstructions.
    • Integrated touch screen to control main system functions by gloved hands
    • Export results to 3D printers to create magnified physical copy of scanned objects
    • GLP (Good Laboratory Practice) software package
    • Software for 2D/3D image analysis, bone morphology and realistic visualization
    • X-ray source
    • Continuously variable 20-100 kV micro-focus X-ray source, automatic 6-position filter changer
    • X-ray detector
      11 Megapixel (4032 x 2688) 14-bit cooled digital X-ray CCD camera with fibre-optic coupling to scintillator, 2×2, 4×4, 8×8 binning modes
    • 6-positions automatic filter changer for energy selection
      No filter, Al 0.2mm, Al 0.5mm, Al 1mm, Al 0.5mm + Cu 0.03mm, Cu 0.1mm (all filters > 99.9% purity)
    • Resolution
      2.8 µm smallest pixel size, 5-6 µm details resolved with more than 10% contrast
    • Max Scanning diameter
      up to 80mm
    • Scan length
      up to 300mm (20mm in one scan)
    • Physiological Monitoring
      real-time motion detection (5 Mp color camera), ECG, breathing detection, temperature stabilization, all signals digitized in 16bit with up to 120 samples/sec
    • Radiation safety
      < 1 µSv/h at any point on the instrument surface during scanning

    For the latest releases of the SkyScan software please visit SkyScan’s website.

    If you need any assistance please contact us at 1-866-334-4674 or

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