DEXA for Bone Mineral Density Research

DEXA scanning has become the most common method for measuring bone mineral density (BMD) of small animals in metabolic bone disease research. Laboratory rats and mice are frequently used as animal models in osteoporosis research and other bone related studies.

  • Osteoporosis research utilizing rats and mice includes hormonal interventions (ovariectomy, orchidectomy, hypophysectomy, parathyroidectomy), immobilization, and dietary manipulations.
  • Rat and mouse skeletons are studied extensively by DEXA because of the similarities in physiopathologic responses between human and rat/mouse skeletons.

Measurement

The InAlyzer displays a live image of the interior of the unit so you can monitor your study animal while the high and low energy images are acquired.

Results

The software has windows for displaying bone, lean, and fat or a composition of them all. Results for the total animal are calculated and displayed on the left.

DEXA ROI function

Data from the Region of Interest (ROI)

Multiple regions of interest can be drawn for analysis of different areas of the animal, such as each hindlimb or the spine. Multiple excised samples could also be scanned at once and ROIs used for analysis of each specimen.

DEXA bone multiple measurement

Multiple bone measurements

The DEXA InAlyzer is a fan-beam device using super flattening technique and can be used to measure several animals at the same time or by analyzing results using ROI on each animal.

Related Articles

What is DEXA?

DEXA (DXA) or Dual Energy X-Ray Absorptiometry is a non-invasive imaging modality based on exploiting the difference in the X-Ray attenuation of tissue and bone

Bone Mineral Density: Volumetric versus Areal

Volumetric density is mathematically defined as the mass per unit volume, i.e grams/cm3. Areal density, is derived from area based measurements and thus has units

Not sure if DEXA will work for your application?
Do you want to see DEXA results from your sample?
Our specialists are happy to help.

Not sure if DEXA will work for your application?
Do you want to see DEXA results from your sample?
Our specialists are happy to help.

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    DEXA Buyers' Guide






      Free DEXA Evaluation Scan

      Are you interested in DEXA scanning but aren’t sure if it will work for your application?  We would be happy to help you determine if an InAlyer DEXA system is right for you and suited for your application. Our Micro Photonics Laboratory has an InAlyzer DEXA system available for a thorough investigation of your sample.

      Request DEXA scan

      Send in a sample and our DEXA experts will do the rest. We will measure bone mineral density or body composition, based on your sample and the results you are seeking.

      Because we cannot accept live animals at this time, we are accepting:

      • Soft tissue sample in preservative
      • Bone specimen

      Fill out the form below and will we contact you to arrange your free DEXA scan.







        Talk to a DEXA specialist about your application

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